Know more

About cookies

What is a "cookie"?

A "cookie" is a piece of information, usually small and identified by a name, which may be sent to your browser by a website you are visiting. Your web browser will store it for a period of time, and send it back to the web server each time you log on again.

Different types of cookies are placed on the sites:

  • Cookies strictly necessary for the proper functioning of the site
  • Cookies deposited by third party sites to improve the interactivity of the site, to collect statistics

Learn more about cookies and how they work

The different types of cookies used on this site

Cookies strictly necessary for the site to function

These cookies allow the main services of the site to function optimally. You can technically block them using your browser settings but your experience on the site may be degraded.

Furthermore, you have the possibility of opposing the use of audience measurement tracers strictly necessary for the functioning and current administration of the website in the cookie management window accessible via the link located in the footer of the site.

Technical cookies

Name of the cookie


Shelf life

CAS and PHP session cookies

Login credentials, session security



Saving your cookie consent choices

12 months

Audience measurement cookies (AT Internet)

Name of the cookie


Shelf life


Trace the visitor's route in order to establish visit statistics.

13 months


Store the anonymous ID of the visitor who starts the first time he visits the site

13 months


Identify the numbers (unique identifiers of a site) seen by the visitor and store the visitor's identifiers.

13 months

About the AT Internet audience measurement tool :

AT Internet's audience measurement tool Analytics is deployed on this site in order to obtain information on visitors' navigation and to improve its use.

The French data protection authority (CNIL) has granted an exemption to AT Internet's Web Analytics cookie. This tool is thus exempt from the collection of the Internet user's consent with regard to the deposit of analytics cookies. However, you can refuse the deposit of these cookies via the cookie management panel.

Good to know:

  • The data collected are not cross-checked with other processing operations
  • The deposited cookie is only used to produce anonymous statistics
  • The cookie does not allow the user's navigation on other sites to be tracked.

Third party cookies to improve the interactivity of the site

This site relies on certain services provided by third parties which allow :

  • to offer interactive content;
  • improve usability and facilitate the sharing of content on social networks;
  • view videos and animated presentations directly on our website;
  • protect form entries from robots;
  • monitor the performance of the site.

These third parties will collect and use your browsing data for their own purposes.

How to accept or reject cookies

When you start browsing an eZpublish site, the appearance of the "cookies" banner allows you to accept or refuse all the cookies we use. This banner will be displayed as long as you have not made a choice, even if you are browsing on another page of the site.

You can change your choices at any time by clicking on the "Cookie Management" link.

You can manage these cookies in your browser. Here are the procedures to follow: Firefox; Chrome; Explorer; Safari; Opera

For more information about the cookies we use, you can contact INRAE's Data Protection Officer by email at or by post at :


24, chemin de Borde Rouge -Auzeville - CS52627 31326 Castanet Tolosan cedex - France

Last update: May 2021

Menu Logo TULIP Nouveau bandeau tutelles EN


Brenda Winkel « Visiting Scientist » seminar

01.29.2020 - Marc-Ridet conference room (INRAE Auzeville campus)

Brenda Winkel « Visiting Scientist » seminar
Brenda Winkel will give a seminar « Watching the clock: Evidence that flavonoids affect the circadian circuitry of plants » on wednesday january 29th at 11:00 in the Marc-Ridet conference room (INRAE Auzeville campus)

Over the past 25 years the Winkel laboratory has helped establish the flavonoid pathway as a model for studying the macromolecular and intracellular organization of plant metabolism. They were the first to demonstrate direct protein interactions among flavonoid enzymes and also uncovered the unexpected localization of flavonoid enzymes in the nucleus.  Most recently, they showed that the entry-point enzyme, chalcone synthase (CHS), interacts with components of the histone remodeling machinery that may offer a new explanation for the connection between flavonoid enzymes and defense.  

Winkel photo

To further explore the potential impact of CHS on gene expression, an RNA-seq dataset was generated for an Arabidopsis tt4 mutant line, which lacks the enzyme and is devoid of flavonoids.  This experiment identified numerous transcripts with altered levels in tt4 seedlings.  Surprisingly, a substantial number of these encode components of the core circadian clock, including the key transcriptional regulators, CCA1 and TOC1.  Analysis of CCA1p::luciferase and TOC1p::luciferase reporter constructs further showed that the amplitude, but not the phase, of the circadian cycle is altered in CHS-deficient seedlings.  Similar effects were observed for a tt7 mutant allele, which affects an intermediate step in flavonoid metabolism, implicating dihydroxy flavonoids rather than the CHS enzyme in modulation of the clock.  Current experiments are aimed at understanding the mechanisms underlying this intriguing newly-discovered connection between flavonoids and the circadian circuitry in plants, which has recently also been reported in animal systems.

Bio: Brenda Winkel is a Professor and former Head of Biological Sciences at Virginia Tech in the U.S. She is currently on Research Leave as a TULIP Visiting Scientist with Elodie Gaulin in the IPM team of Bernard Dumas.