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A Selective Bottleneck During Host Entry Drives the Evolution of New Legume Symbionts

A Selective Bottleneck During Host Entry Drives the Evolution of New Legume Symbionts

Researchers from LRSV and LIPME, published a paper in Molecular Biology and Evolution in May, an article that showed that the entry into the host plant is the major selective force acting on these bacterial populations. They also identified many adaptive mutations, that will fuel future work aiming at understanding the molecular bases of adaptation in their system.

"This paper is a collaboration between 2 Tulip labs (LIPME and EDB). We analysed the evolutionary dynamics of bacterial populations during the experimental evolution of a plant pathogen into a legume symbiont. Using a combination of whole-population sequencing, bacterial genetics and mathematical modeling, we showed that the entry into the host plant is the major selective force acting on these bacterial populations.

We also identified many adaptive mutations, that will fuel future work aiming at understanding the molecular bases of adaptation in our system”

See also

Ginaini Grazielli Doin de Moura, Saida Mouffok, Nil Gaudu, Anne-Claire Cazalé, Marine Milhes, Tabatha Bulach, Sophie Valière, David Roche, Jean-Baptiste Ferdy, Catherine Masson-Boivin, Delphine Capela, Philippe Remigi
Molecular Biology and Evolution, Volume 40, Issue 5, May 2023, msad116, https://doi.org/10.1093/molbev/msad116
A Selective Bottleneck During Host Entry Drives the Evolution of New Legume Symbionts,

Modification date : 25 January 2024 | Publication date : 25 January 2024 | Redactor : Tulip Communication, Philippe Remigi