How Arabidopsis thaliana regulates gene expression and represses transposable element

An international study conducted on the Arabidopsis thaliana plant shows that the PMD/PP7L protein complex, formed by the interaction of the MAIN and MAIL1 proteins with the PP7L protein (a phosphoprotein phosphatase), is an essential link in the repression of transposable elements (TEs) and the correct expression of genes. This mechanism thus makes it possible to preserve cellular integrity. The results of this research, notably conducted by the LGDP (UMR CNRS/UPVD), were published in April 2020 in the journal PLoS Genetics.

The CNRS commented on those results in a short article entitled "Le complexe protéique PMD/PP7L régule l'expression des gènes et transposons chez Arabidopsis" (“The PMD/PP7L protein complex regulates gene expression and transposons for Arabidopsis”). Read the article (French only)

Publication Nicolau et al. (2020) - PLoS Genetics - The plant mobile domain proteins MAIN and MAIL1 interact with the phosphatase PP7L to regulate gene expression and silence transposable elements in Arabidopsis thaliana.
Nicolau M, Picault N, Descombin J, Jami-Alahmadi Y, Feng S, Bucher E, Jacobsen SE, Deragon JM, Wohlschlegel J, Moissiard G. PLoS Genet. 2020 Apr 14;16(4):e1008324. doi: 10.1371/journal.pgen.1008324. eCollection 2020 Apr

Modification date : 07 June 2023 | Publication date : 02 December 2021 | Redactor : TULIP Communication