Les protéines du domaine mobile des plantes assurent l'expression de Microrchidia 1 pour réaliser le silençage des transposons.

Les chercheurs du LGDP ont publié en février dans Life Science Alliance. Une étude qui a révélé l'interaction subtile entre les voies PMD et MORC1 pour réprimer efficacement les TEs.

"TThe Plant Mobile Domain (PMD) proteins MAIN and MAIL1 interact together to regulate gene expression and repress transposable elements (TEs) in Arabidopsis. In a recent study published in Life Science Alliance, our group at LGDP showed that MAIN and MAIL1 are required for the proper expression of the chromatin factor Microrchidia 1 (MORC1), which is involved in TE silencing.

Through the study of pmd and morc1 high order mutants, we showed the combining the mutations does not exacerbate TE silencing defects, while rescuing MORC1 expression in the pmd mutants is sufficient to reestablish TE silencing at a subset of loci. Thus, this study reveals the subtle interplay between PMD and MORC1 pathways to efficiently repress TEs."

Voir aussi

Lucas Jarry, Julie Descombin, Melody Nicolau, Ange Dussutour, Nathalie Picault, Guillaume Moissiard
Life Science Alliance, Volume 6, No. 4, April 2023, https://doi.org/10.26508/lsa.202201539
Plant mobile domain proteins ensure Microrchidia 1 expression to fulfill transposon silencing