Les peptides complémentaires représentent une alternative crédible aux produits agrochimiques en activant la traduction des protéines ciblées.

Des chercheurs du LGDP et du LRSV ont publié en janvier leurs résultats dans Nature Communications, montrant que des peptides complémentaires (cPEP) provenant de n'importe quel gène peuvent être conçus pour cibler spécifiquement les gènes codant pour les plantes.

"The current agriculture main challenge is to maintain food production while facing multiple threats such as increasing world population, temperature increase, lack of agrochemicals due to health issues and uprising of weeds resistant to herbicides. Developing novel, alternative, and safe methods is hence of paramount importance.

Here, we show that complementary peptides (cPEPs) from any gene can be designed to target specifically plant coding genes. External application of synthetic peptides increases the abundance of the targeted protein, leading to related phenotypes.

Moreover, we provide evidence that cPEPs can be powerful tools in agronomy to improve plant traits, such as growth, resistance to pathogen or heat stress, without the needs of genetic approaches. Finally, by combining their activity they can also be used to reduce weed growth."

Voir aussi

Ormancey M, Guillotin B, Merret R, Camborde L, Duboé C, Fabre B, Pouzet C, Impens F, Van Haver D, Carpentier MC, Clemente HS, Aguilar M, Lauressergues D, Scharff LB, Pichereaux C, Burlet-Schiltz O, Bousquet-Antonelli C, Gevaert K, Thuleau P, Plaza S, Combier JP. (2023)
Complementary peptides represent a credible alternative to agrochemicals by activating translation of targeted proteins. Nat Commun. 2023 Jan 17;14(1):254. https://doi.org/10.1038/s41467-023-35951-0

Date de modification : 29 janvier 2024 | Date de création : 23 janvier 2024 | Rédaction : Tulip Communication, Jean-Philippe Combier